Slacker actress Jane (Anna Faris), is having a bad day that is getting more outrageous by the minute. Jane's misadventures begin when she treats herself to a batch of cupcakes left unattended by her psycho roommate that prove not as innocent as they appear. She then bums a ride from her roommate's friend (John Krasinski) and attempts to cross town so she can repay an unforgiving drug dealer, attend an audition, and somehow replace the precious cupcakes.